Population Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Target Attainment Analysis for Solithromycin to Support Intravenous Dose Selection in Patients with Community-Acquired Bacterial Pneumonia
نویسندگان
چکیده
with Community-Acquired Bacterial Pneumonia O. O. Okusanya1, S. M. Bhavnani1, A. Forrest1, C. C. Bulik1, B. Jamieson2, D. Oldach2, P. Fernandes2, P. G. Ambrose1 1Institute for Clinical Pharmacodynamics, Latham, NY; 2Cempra Pharmaceuticals, Chapel Hill, NC Abstract Materials and Methods Results Olanrewaju O. Okusanya, Pharm.D., M.S., BCPS Institute for Clinical Pharmacodynamics 43 British American Blvd. Latham, NY 12110 Phone: (518) 429-2600 Email: [email protected]
منابع مشابه
Pharmacokinetic/pharmacodynamic target attainment of intravenous β-lactam regimens against Gram-negative bacteria isolated in a Brazilian teaching hospital.
INTRODUCTION Monte Carlo simulations have been used for selecting optimal antibiotic regimens for treatment of bacterial infections. The aim of this study was to assess the pharmacokinetic and pharmacodynamic target attainment of intravenous β-lactam regimens commonly used to treat bloodstream infections (BSIs) caused by Gram-negative rod-shaped organisms in a Brazilian teaching hospital. MET...
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